CARDIAC CONDUCTION INTERACTIONS OF PROPRANOLOL AND VERAPAMIL WITH HALOTHANE IN PENTOBARBITONE-ANAESTHETIZED DOGS
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چکیده
منابع مشابه
Cardiovascular and respiratory effects of epidural lidocaine and morphine administered in dogs anaesthetized with halothane
Extradural co-administration of opioids and local anaesthetics is a popular method for control of pain [3, 5, 18]. Spinal and epidural administration of opioids produce a profound and long lasting segmental analgesia, which is not associated with sensory, sympathetic, or motor blockade [2, 4]. The side effects of epidural opioids in men are dose-dependent and may include pruritus, nausea, respi...
متن کاملEffect of oxprenolol on adrenaline-evoked ventricular arrhythmias in dogs anaesthetized with halothane in oxygen.
The effect of oxprenolol (CIBA 39,089-Ba), a recently introduced adrenergic betareceptor antagonist, on adrenaline-evoked ventricular arrhythmias was studied in atropinized dogs anaesthetized with halothane in oxygen. The anti-arrhythmic activity of oxprenolol was due to specific blockade of beta-receptors. The block produced was surmountable in nature and larger doses of adrenaline re-evoked v...
متن کاملThe effects of propranolol on cardiac conduction.
was used as a measure of A-V conduction and the interval from the His bundle electrogram to the S wave (H-S interval) was used as a measure of intraventricular conduction. Propranolol significantly prolonged the P-H interval in every patient at all paced heart rates, and it had no effect on the H-S interval. In two patients propranolol prolonged the effective refractory period of the atrioventr...
متن کاملEffects of Verapamil and Propranolol
The ,3-adrenergic and calcium channel blocking agents are known to reduce heart rate and alter myocardial contractility. More recent evidence suggests that both agents affect the metabolic consequences of ischemia, independent of their effects on heart rate and contractility. We used a low-flow model of ischemia in swine with heart rate held constant by atrial pacing. Blood was shunted from the...
متن کاملEffects of Verapamil and Propranolol
To determine the effects of verapamil on left ventricular (LV) systolic function and diastolic filling in patients with coronary artery disease (CAD), we performed gated radionuclide angiography at rest and during exercise in 16 symptomatic patients before and during oral verapamil therapy (480 mg/day). Twelve patients were also studied during oral propranolol (160-320 mg/day). LV ejection frac...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1988
ISSN: 0007-0912
DOI: 10.1093/bja/61.6.748